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keep track of carefully (1)amobarbital will minimize the level or effect of exemestane by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/check. For clients receiving exemestane that has a strong CYP3A4 inducer the advisable dose of exemestane is 50 mg day-to-day after a food. dexamethasone will decrease the level or effect of e